No, SMTP port TCP 25 is blocked for OUTBOUND use, for network security reasons for all new VPS accounts. Port 25 Inbound is not blocked so your VPS can receive emails.
If possible for mail relay use secure protocol ports like 465 or 587.
Also use dedicated mailing services for Mass Mailing and Email Marketing Purposes.
Here are some recommendations:
- https://sendpulse.com - SendPluse offers free send of 12.000 emails/month to send via SMTP relay or Web API. Unlimited mail sending for 7.2 Euro/month
- https://www.mailjet.com
- https://sendgrid.com
- https://postmarkapp.com
- https://www.mailgun.com
- https://sendgrid.com
- https://mailchimp.com